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Fragile X mental retardation protein expression in Alzheimer’s disease

The FMR1 protein product, FMRP, is an mRNA binding protein associated with translational inhibition of target transcripts. One FMRP target is the amyloid precursor protein (APP) mRNA, and APP levels are elevated in Fmr1 KO mice. Given that elevated APP protein expression can elicit Alzheimer’s disea...

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Detalles Bibliográficos
Autores principales:	Renoux, Abigail J., Carducci, Nicholas M., Ahmady, Arya A., Todd, Peter K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2014
Materias:	Pediatrics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4233940/ https://www.ncbi.nlm.nih.gov/pubmed/25452762 http://dx.doi.org/10.3389/fgene.2014.00360

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