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Transcriptome-Wide Analysis of Messenger RNA Decay in Normal and Osteoarthritic Human Articular Chondrocytes

OBJECTIVE: Messenger RNA (mRNA) decay rates control not only gene expression levels, but also responsiveness to altered transcriptional input. We undertook this study to examine transcriptome-wide posttranscriptional regulation in both normal and osteoarthritic (OA) human articular chondrocytes. MET...

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Detalles Bibliográficos
Autores principales:	Tew, Simon R, McDermott, Benjamin T, Fentem, Rory B, Peffers, Mandy J, Clegg, Peter D
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2014
Materias:	Osteoarthritis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4233952/ https://www.ncbi.nlm.nih.gov/pubmed/25155964 http://dx.doi.org/10.1002/art.38849

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