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Two- and Three-dimensional Rings in Drugs

Using small, flat aromatic rings as components of fragments or molecules is a common practice in fragment-based drug discovery and lead optimization. With an increasing focus on the exploration of novel biological and chemical space, and their improved synthetic accessibility, 3D fragments are attra...

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Detalles Bibliográficos
Autores principales:	Aldeghi, Matteo, Malhotra, Shipra, Selwood, David L, Chan, Ah Wing Edith
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2014
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4233953/ https://www.ncbi.nlm.nih.gov/pubmed/24472495 http://dx.doi.org/10.1111/cbdd.12260

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