Loss of PPARγ expression in mammary secretory epithelial cells creates a pro-breast tumorigenic environment

Breast cancer is the leading cause of new cancer diagnoses among women. Using peroxisome proliferator-activated receptor (PPAR)γ((+/−)) mice, we showed normal expression of PPARγ was critical to stop 7,12-dimethylbenz[a]anthracene (DMBA)-induced breast tumorigenesis. PPARγ is expressed in many breas...

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Detalles Bibliográficos
Autores principales: Apostoli, Anthony J, Skelhorne-Gross, Graham EA, Rubino, Rachel E, Peterson, Nichole T, Di Lena, Michael A, Schneider, Mark M, SenGupta, Sandip K, Nicol, Christopher JB
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Carcinogenesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4233966/
https://www.ncbi.nlm.nih.gov/pubmed/23934545
http://dx.doi.org/10.1002/ijc.28432

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4233966/
https://www.ncbi.nlm.nih.gov/pubmed/23934545
http://dx.doi.org/10.1002/ijc.28432

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