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Progressive multifocal cerebral infarction in a young kidney transplant recipient due to thrombotic microangiopathy
BACKGROUND: Renal transplant recipients frequently experience neurological complications. Whereas ischemic stroke, cerebral haemorrhage or hypertensive encephalopathy often result from vascular alterations prior to transplantation, other cerebral diseases like CNS infections, primary brain tumors an...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4234137/ https://www.ncbi.nlm.nih.gov/pubmed/24708483 http://dx.doi.org/10.1186/1471-2369-15-59 |
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author | Haghikia, Arash Heeren, Meike Bockmeyer, Clemens Haubitz, Bernd Gwinner, Wilfried |
author_facet | Haghikia, Arash Heeren, Meike Bockmeyer, Clemens Haubitz, Bernd Gwinner, Wilfried |
author_sort | Haghikia, Arash |
collection | PubMed |
description | BACKGROUND: Renal transplant recipients frequently experience neurological complications. Whereas ischemic stroke, cerebral haemorrhage or hypertensive encephalopathy often result from vascular alterations prior to transplantation, other cerebral diseases like CNS infections, primary brain tumors and drug induced neurotoxicity may develop as consequences of the required post-transplant immunosuppressive treatment. CASE PRESENTATION: Here we report on an unusual clinical course of a young kidney transplant recipient with a cluster of fulminant necrotic brain lesions within a period of two months due to thrombotic microangiopathy. CONCLUSION: Cerebral ischemia in organ transplant recipients should prompt one to consider thrombotic microangiopathy. |
format | Online Article Text |
id | pubmed-4234137 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-42341372014-11-18 Progressive multifocal cerebral infarction in a young kidney transplant recipient due to thrombotic microangiopathy Haghikia, Arash Heeren, Meike Bockmeyer, Clemens Haubitz, Bernd Gwinner, Wilfried BMC Nephrol Case Report BACKGROUND: Renal transplant recipients frequently experience neurological complications. Whereas ischemic stroke, cerebral haemorrhage or hypertensive encephalopathy often result from vascular alterations prior to transplantation, other cerebral diseases like CNS infections, primary brain tumors and drug induced neurotoxicity may develop as consequences of the required post-transplant immunosuppressive treatment. CASE PRESENTATION: Here we report on an unusual clinical course of a young kidney transplant recipient with a cluster of fulminant necrotic brain lesions within a period of two months due to thrombotic microangiopathy. CONCLUSION: Cerebral ischemia in organ transplant recipients should prompt one to consider thrombotic microangiopathy. BioMed Central 2014-04-07 /pmc/articles/PMC4234137/ /pubmed/24708483 http://dx.doi.org/10.1186/1471-2369-15-59 Text en Copyright © 2014 Haghikia et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. |
spellingShingle | Case Report Haghikia, Arash Heeren, Meike Bockmeyer, Clemens Haubitz, Bernd Gwinner, Wilfried Progressive multifocal cerebral infarction in a young kidney transplant recipient due to thrombotic microangiopathy |
title | Progressive multifocal cerebral infarction in a young kidney transplant recipient due to thrombotic microangiopathy |
title_full | Progressive multifocal cerebral infarction in a young kidney transplant recipient due to thrombotic microangiopathy |
title_fullStr | Progressive multifocal cerebral infarction in a young kidney transplant recipient due to thrombotic microangiopathy |
title_full_unstemmed | Progressive multifocal cerebral infarction in a young kidney transplant recipient due to thrombotic microangiopathy |
title_short | Progressive multifocal cerebral infarction in a young kidney transplant recipient due to thrombotic microangiopathy |
title_sort | progressive multifocal cerebral infarction in a young kidney transplant recipient due to thrombotic microangiopathy |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4234137/ https://www.ncbi.nlm.nih.gov/pubmed/24708483 http://dx.doi.org/10.1186/1471-2369-15-59 |
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