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Modulation of sphingosine-1-phosphate and apolipoprotein M levels in the plasma, liver and kidneys in streptozotocin-induced diabetic mice

AIMS/INTRODUCTION: Sphingosine-1-phosphate (S1P), a multifunctional bioactive lipid mediator, is involved in various diseases. Apolipoprotein M (ApoM) carries S1P on high-density lipoprotein and modulates S1P metabolism to increase the total S1P mass in the body. Both S1P and ApoM are involved in di...

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Detalles Bibliográficos
Autores principales: Nojiri, Takahiro, Kurano, Makoto, Tokuhara, Yasunori, Ohkubo, Shigeo, Hara, Masumi, Ikeda, Hitoshi, Tsukamoto, Kazuhisa, Yatomi, Yutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4234226/
https://www.ncbi.nlm.nih.gov/pubmed/25422763
http://dx.doi.org/10.1111/jdi.12232