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Modulation of sphingosine-1-phosphate and apolipoprotein M levels in the plasma, liver and kidneys in streptozotocin-induced diabetic mice
AIMS/INTRODUCTION: Sphingosine-1-phosphate (S1P), a multifunctional bioactive lipid mediator, is involved in various diseases. Apolipoprotein M (ApoM) carries S1P on high-density lipoprotein and modulates S1P metabolism to increase the total S1P mass in the body. Both S1P and ApoM are involved in di...
Autores principales: | Nojiri, Takahiro, Kurano, Makoto, Tokuhara, Yasunori, Ohkubo, Shigeo, Hara, Masumi, Ikeda, Hitoshi, Tsukamoto, Kazuhisa, Yatomi, Yutaka |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4234226/ https://www.ncbi.nlm.nih.gov/pubmed/25422763 http://dx.doi.org/10.1111/jdi.12232 |
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