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Exome-Wide Somatic Microsatellite Variation Is Altered in Cells with DNA Repair Deficiencies
Microsatellites (MST), tandem repeats of 1–6 nucleotide motifs, are mutational hot-spots with a bias for insertions and deletions (INDELs) rather than single nucleotide polymorphisms (SNPs). The majority of MST instability studies are limited to a small number of loci, the Bethesda markers, which ar...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4234249/ https://www.ncbi.nlm.nih.gov/pubmed/25402475 http://dx.doi.org/10.1371/journal.pone.0110263 |