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Lyme arthritis in Southern Norway - an endemic area for Lyme Borreliosis
BACKGROUND: Despite Southern Norway is an endemic area for Lyme borreliosis there is a lack of data on Lyme arthritis (LA). In the literature controversies exist if acute LA can develop into chronic arthritis. Our objective was to identify and characterize patients with LA in Southern Norway and exp...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4234297/ https://www.ncbi.nlm.nih.gov/pubmed/24708707 http://dx.doi.org/10.1186/1471-2334-14-185 |
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author | Haugeberg, Glenn Hansen, Inger Johanne W Skarpaas, Tone Noraas, Sølvi Kjelland, Vivian |
author_facet | Haugeberg, Glenn Hansen, Inger Johanne W Skarpaas, Tone Noraas, Sølvi Kjelland, Vivian |
author_sort | Haugeberg, Glenn |
collection | PubMed |
description | BACKGROUND: Despite Southern Norway is an endemic area for Lyme borreliosis there is a lack of data on Lyme arthritis (LA). In the literature controversies exist if acute LA can develop into chronic arthritis. Our objective was to identify and characterize patients with LA in Southern Norway and explore disease course after antibiotic treatment. METHODS: Patients aged 20 years or older with arthritis and a positive serology for Borrelia burgdorferi infection (IgG and/or IgM) suspected of having LA were consecutively recruited either from general practitioners or from hospital departments. RESULTS: From January 2007 to December 2010 a total of 27 patients were assessed. Mean (range) age was 56 years (41–80) and mean symptom duration prior to inclusion was 11.2 weeks (1 day – 2 years). Definite LA was diagnosed in 16 patients, probable LA in 5 patients and 6 patients were concluded to have other arthritis disorders. Among the 21 LA patients 20 had mono-arthritis (knee 18, ankle 2) and 1 had polyarthritis. All LA patients responded favourable to antibiotic treatment and none of the patients developed chronic arthritis after long term follow up, not even in LA patients who had intraarticular glucocorticosteroid (GC) injection prior to antibiotic treatment. CONCLUSIONS: Our data shows that LA in Southern Norway is a benign disease which successfully can be treated with antibiotics even in patients treated with GC prior to antibiotics. |
format | Online Article Text |
id | pubmed-4234297 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-42342972014-11-18 Lyme arthritis in Southern Norway - an endemic area for Lyme Borreliosis Haugeberg, Glenn Hansen, Inger Johanne W Skarpaas, Tone Noraas, Sølvi Kjelland, Vivian BMC Infect Dis Research Article BACKGROUND: Despite Southern Norway is an endemic area for Lyme borreliosis there is a lack of data on Lyme arthritis (LA). In the literature controversies exist if acute LA can develop into chronic arthritis. Our objective was to identify and characterize patients with LA in Southern Norway and explore disease course after antibiotic treatment. METHODS: Patients aged 20 years or older with arthritis and a positive serology for Borrelia burgdorferi infection (IgG and/or IgM) suspected of having LA were consecutively recruited either from general practitioners or from hospital departments. RESULTS: From January 2007 to December 2010 a total of 27 patients were assessed. Mean (range) age was 56 years (41–80) and mean symptom duration prior to inclusion was 11.2 weeks (1 day – 2 years). Definite LA was diagnosed in 16 patients, probable LA in 5 patients and 6 patients were concluded to have other arthritis disorders. Among the 21 LA patients 20 had mono-arthritis (knee 18, ankle 2) and 1 had polyarthritis. All LA patients responded favourable to antibiotic treatment and none of the patients developed chronic arthritis after long term follow up, not even in LA patients who had intraarticular glucocorticosteroid (GC) injection prior to antibiotic treatment. CONCLUSIONS: Our data shows that LA in Southern Norway is a benign disease which successfully can be treated with antibiotics even in patients treated with GC prior to antibiotics. BioMed Central 2014-04-05 /pmc/articles/PMC4234297/ /pubmed/24708707 http://dx.doi.org/10.1186/1471-2334-14-185 Text en Copyright © 2014 Haugeberg et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Research Article Haugeberg, Glenn Hansen, Inger Johanne W Skarpaas, Tone Noraas, Sølvi Kjelland, Vivian Lyme arthritis in Southern Norway - an endemic area for Lyme Borreliosis |
title | Lyme arthritis in Southern Norway - an endemic area for Lyme Borreliosis |
title_full | Lyme arthritis in Southern Norway - an endemic area for Lyme Borreliosis |
title_fullStr | Lyme arthritis in Southern Norway - an endemic area for Lyme Borreliosis |
title_full_unstemmed | Lyme arthritis in Southern Norway - an endemic area for Lyme Borreliosis |
title_short | Lyme arthritis in Southern Norway - an endemic area for Lyme Borreliosis |
title_sort | lyme arthritis in southern norway - an endemic area for lyme borreliosis |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4234297/ https://www.ncbi.nlm.nih.gov/pubmed/24708707 http://dx.doi.org/10.1186/1471-2334-14-185 |
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