Cell Fate Decisions in Malignant Hematopoiesis: Leukemia Phenotype Is Determined by Distinct Functional Domains of the MN1 Oncogene

Extensive molecular profiling of leukemias and preleukemic diseases has revealed that distinct clinical entities, like acute myeloid (AML) and T-lymphoblastic leukemia (T-ALL), share similar pathogenetic mutations. It is not well understood how the cell of origin, accompanying mutations, extracellul...

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Detalles Bibliográficos
Autores principales: Lai, Courteney K., Moon, Yeonsook, Kuchenbauer, Florian, Starzcynowski, Daniel T., Argiropoulos, Bob, Yung, Eric, Beer, Philip, Schwarzer, Adrian, Sharma, Amit, Park, Gyeongsin, Leung, Malina, Lin, Grace, Vollett, Sarah, Fung, Stephen, Eaves, Connie J., Karsan, Aly, Weng, Andrew P., Humphries, R. Keith, Heuser, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4234417/
https://www.ncbi.nlm.nih.gov/pubmed/25401736
http://dx.doi.org/10.1371/journal.pone.0112671

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