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Plasmodium falciparum UvrD activities are downregulated by DNA-interacting compounds and its dsRNA inhibits malaria parasite growth

BACKGROUND: Human malaria parasite infection and its control is a global challenge which is responsible for ~0.65 million deaths every year globally. The emergence of drug resistant malaria parasite is another challenge to fight with malaria. Enormous efforts are being made to identify suitable drug...

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Detalles Bibliográficos
Autores principales: Tarique, Mohammed, Tabassum, Farha, Ahmad, Moaz, Tuteja, Renu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4234510/
https://www.ncbi.nlm.nih.gov/pubmed/24707807
http://dx.doi.org/10.1186/1471-2091-15-9

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