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The Oncogenic MicroRNA Hsa-miR-155-5p Targets the Transcription Factor ELK3 and Links It to the Hypoxia Response

The molecular response to hypoxia is a critical cellular process implicated in cancer, and a target for drug development. The activity of the major player, HIF1α, is regulated at different levels by various factors, including the transcription factor ELK3. The molecular mechanisms of this intimate c...

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Detalles Bibliográficos
Autores principales: Robertson, E. Douglas, Wasylyk, Christine, Ye, Tao, Jung, Alain C., Wasylyk, Bohdan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4234625/
https://www.ncbi.nlm.nih.gov/pubmed/25401928
http://dx.doi.org/10.1371/journal.pone.0113050