Cargando…
How Does Domain Replacement Affect Fibril Formation of the Rabbit/Human Prion Proteins
BACKGROUND: It is known that in vivo human prion protein (PrP) have the tendency to form fibril deposits and are associated with infectious fatal prion diseases, while the rabbit PrP does not readily form fibrils and is unlikely to cause prion diseases. Although we have previously demonstrated that...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4234653/ https://www.ncbi.nlm.nih.gov/pubmed/25401497 http://dx.doi.org/10.1371/journal.pone.0113238 |