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Wnt5a Suppresses Tumor Formation and Redirects Tumor Phenotype in MMTV-Wnt1 Tumors

Wnt5a is a non-canonical signaling Wnt that has been implicated in tumor suppression. We previously showed that loss of Wnt5a in MMTV-PyVmT tumors resulted in a switch in tumor phenotype resulting in tumors with increased basal phenotype and high Wnt/β-catenin signaling. The object of this study was...

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Detalles Bibliográficos
Autores principales:	Easter, Stephanie L., Mitchell, Elizabeth H., Baxley, Sarah E., Desmond, Renee, Frost, Andra R., Serra, Rosa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4234660/ https://www.ncbi.nlm.nih.gov/pubmed/25401739 http://dx.doi.org/10.1371/journal.pone.0113247

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