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Immunization with advanced glycation end products modified low density lipoprotein inhibits atherosclerosis progression in diabetic apoE and LDLR null mice

BACKGROUND: Diabetes accelerates atherosclerosis through undefined molecular mechanisms. Hyperglycemia induces formation of advanced glycation end product (AGE)-modified low-density lipoprotein (LDL). Anti-AGE-LDL autoantibodies favor atherosclerosis (AS) progression in humans, while anti oxidized L...

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Detalles Bibliográficos
Autores principales:	Zhu, Lin, He, Zhiqing, Wu, Feng, Ding, Ru, Jiang, Qixia, Zhang, Jiayou, Fan, Min, Wang, Xing, Eva, Bengtsson, Jan, Nilsson, Liang, Chun, Wu, Zonggui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Original Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4234834/ https://www.ncbi.nlm.nih.gov/pubmed/25391642 http://dx.doi.org/10.1186/s12933-014-0151-6

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