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MUSIC: identification of enriched regions in ChIP-Seq experiments using a mappability-corrected multiscale signal processing framework

We present MUSIC, a signal processing approach for identification of enriched regions in ChIP-Seq data, available at music.gersteinlab.org. MUSIC first filters the ChIP-Seq read-depth signal for systematic noise from non-uniform mappability, which fragments enriched regions. Then it performs a multi...

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Detalles Bibliográficos
Autores principales:	Harmanci, Arif, Rozowsky, Joel, Gerstein, Mark
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Method
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4234855/ https://www.ncbi.nlm.nih.gov/pubmed/25292436 http://dx.doi.org/10.1186/s13059-014-0474-3

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