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Synergistic Signaling of KRAS and Thyroid Hormone Receptor β Mutants Promotes Undifferentiated Thyroid Cancer through MYC Up-Regulation()()

Undifferentiated thyroid carcinoma is one of the most aggressive human cancers with frequent RAS mutations. How mutations of the RAS gene contribute to undifferentiated thyroid cancer remains largely unknown. Mice harboring a potent dominant negative mutant thyroid hormone receptor β, TRβPV (Thrb(PV...

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Detalles Bibliográficos
Autores principales:	Zhu, Xuguang, Zhao, Li, Park, Jeong Won, Willingham, Mark C., Cheng, Sheue-yann
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Neoplasia Press 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4234871/ https://www.ncbi.nlm.nih.gov/pubmed/25246276 http://dx.doi.org/10.1016/j.neo.2014.08.003

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