Cargando…

Breast Cancer: Coordinated Regulation of CCL2 Secretion by Intracellular Glycosaminoglycans and Chemokine Motifs()()

The chemokine CCL2 (MCP-1) has been identified as a prominent tumor-promoting factor in breast cancer. The major source for CCL2 is in the tumor cells; thus, identifying the mechanisms regulating CCL2 release by these cells may enable the future design of modalities inhibiting CCL2 secretion and con...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lebel-Haziv, Yaeli, Meshel, Tsipi, Soria, Gali, Yeheskel, Adva, Mamon, Elad, Ben-Baruch, Adit
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Neoplasia Press 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4234876/ https://www.ncbi.nlm.nih.gov/pubmed/25246273 http://dx.doi.org/10.1016/j.neo.2014.08.004

Ejemplares similares

Inflammatory mediators in breast cancer: Coordinated expression of TNFα & IL-1β with CCL2 & CCL5 and effects on epithelial-to-mesenchymal transition
por: Soria, Gali, et al.
Publicado: (2011)

Tumor-Promoting Circuits That Regulate a Cancer-Related Chemokine Cluster: Dominance of Inflammatory Mediators Over Oncogenic Alterations
por: Leibovich-Rivkin, Tal, et al.
Publicado: (2012)

Microenvironmental networks promote tumor heterogeneity and enrich for metastatic cancer stem-like cells in Luminal-A breast tumor cells
por: Weitzenfeld, Polina, et al.
Publicado: (2016)

Tumor Cell-Autonomous Pro-Metastatic Activities of PD-L1 in Human Breast Cancer Are Mediated by PD-L1-S283 and Chemokine Axes
por: Erlichman, Nofar, et al.
Publicado: (2022)

Correction: Erlichman et al. Tumor Cell-Autonomous Pro-Metastatic Activities of PD-L1 in Human Breast Cancer Are Mediated by PD-L1-S283 and Chemokine Axes. Cancers 2022, 14, 1042
por: Erlichman, Nofar, et al.
Publicado: (2022)

Tumor-Stroma-Inflammation Networks Promote Pro-metastatic Chemokines and Aggressiveness Characteristics in Triple-Negative Breast Cancer
por: Liubomirski, Yulia, et al.
Publicado: (2019)

Inflammation-Driven Regulation of PD-L1 and PD-L2, and Their Cross-Interactions with Protective Soluble TNFα Receptors in Human Triple-Negative Breast Cancer
por: Baram, Tamir, et al.
Publicado: (2022)

Structural Evidence for the Tetrameric Assembly of Chemokine CCL11 and the Glycosaminoglycan Arixtra™
por: Dykstra, Andrew B., et al.
Publicado: (2013)

Progression of Luminal Breast Tumors Is Promoted by Ménage à Trois between the Inflammatory Cytokine TNFα and the Hormonal and Growth-Supporting Arms of the Tumor Microenvironment
por: Weitzenfeld, Polina, et al.
Publicado: (2013)

Biochemical Analysis of Matrix Metalloproteinase Activation of Chemokines CCL15 and CCL23 and Increased Glycosaminoglycan Binding of CCL16
por: Starr, Amanda E., et al.
Publicado: (2012)

A Tumor Microenvironment-Driven Network Regulated by STAT3 and p65 Negatively Controls the Enrichment of Cancer Stem Cells in Human HR+/HER2− Breast Cancer
por: Ben-Yaakov, Hagar, et al.
Publicado: (2023)

Chemokines and Glycosaminoglycans
por: Proudfoot, Amanda E. I.
Publicado: (2015)

Regulation of the inflammatory profile of stromal cells in human breast cancer: prominent roles for TNF-α and the NF-κB pathway
por: Katanov, Christina, et al.
Publicado: (2015)

Interference with Oligomerization and Glycosaminoglycan Binding of the Chemokine CCL5 Improves Experimental Liver Injury
por: Nellen, Andreas, et al.
Publicado: (2012)

The Cell-Autonomous Pro-Metastatic Activities of PD-L1 in Breast Cancer Are Regulated by N-Linked Glycosylation-Dependent Activation of STAT3 and STAT1
por: Erlichman, Nofar, et al.
Publicado: (2023)

The inflammatory cytokine TNFα cooperates with Ras in elevating metastasis and turns WT-Ras to a tumor-promoting entity in MCF-7 cells
por: Leibovich-Rivkin, Tal, et al.
Publicado: (2014)

Co-Inflammatory Roles of TGFβ1 in the Presence of TNFα Drive a Pro-inflammatory Fate in Mesenchymal Stem Cells
por: Lerrer, Shalom, et al.
Publicado: (2017)

Notch-Mediated Tumor-Stroma-Inflammation Networks Promote Invasive Properties and CXCL8 Expression in Triple-Negative Breast Cancer
por: Liubomirski, Yulia, et al.
Publicado: (2019)

Continuous Inflammatory Stimulation Leads via Metabolic Plasticity to a Prometastatic Phenotype in Triple-Negative Breast Cancer Cells
por: Morein, Dina, et al.
Publicado: (2021)

Targeting Chemokine—Glycosaminoglycan Interactions to Inhibit Inflammation
por: Crijns, Helena, et al.
Publicado: (2020)

Perspectives on the Biological Role of Chemokine:Glycosaminoglycan Interactions
por: Handel, Tracy M., et al.
Publicado: (2020)

The Activity of CCL18 is Principally Mediated through Interaction with Glycosaminoglycans
por: Krohn, Sonja, et al.
Publicado: (2013)

Reduced expression of chemokine (C-C motif) ligand-2 (CCL2) in ovarian adenocarcinoma
por: Arnold, J M, et al.
Publicado: (2005)

C-C Motif Chemokine Ligand 5 (CCL5) Promotes Irradiation-Evoked Osteoclastogenesis
por: Wang, Jing, et al.
Publicado: (2023)

Beyond Cell Motility: The Expanding Roles of Chemokines and Their Receptors in Malignancy
por: Morein, Dina, et al.
Publicado: (2020)

Revisiting CCL-type chemokines in breast cancer and its milieu: prominent targetable chemokines, CCL8 and CCL21
por: Unver, Nese
Publicado: (2021)

Persistent Inflammatory Stimulation Drives the Conversion of MSCs to Inflammatory CAFs That Promote Pro-Metastatic Characteristics in Breast Cancer Cells
por: Rubinstein-Achiasaf, Linor, et al.
Publicado: (2021)

Chemotherapy Shifts the Balance in Favor of CD8+ TNFR2+ TILs in Triple-Negative Breast Tumors
por: Baram, Tamir, et al.
Publicado: (2021)

Heparin Specifically Interacts with Basic BBXB Motifs of the Chemokine CCL21 to Define CCR7 Signaling
por: Artinger, Marc, et al.
Publicado: (2023)

CC chemokines CCL2, CCL3, CCL4 and CCL5 are elevated in osteoporosis patients
por: Farangis, Fatehi, et al.
Publicado: (2017)

Glycosaminoglycan Interactions with Chemokines Add Complexity to a Complex System
por: Proudfoot, Amanda E. I., et al.
Publicado: (2017)

The Anti-inflammatory Protein TSG-6 Regulates Chemokine Function by Inhibiting Chemokine/Glycosaminoglycan Interactions
por: Dyer, Douglas P., et al.
Publicado: (2016)

Genetic Association of the C-C Motif Chemokine Ligand 2 (CCL2) rs1024611 Polymorphism With Periodontitis
por: Ahmed Khan, Hooriyah Laiq, et al.
Publicado: (2023)

Chemokine CXCL1 mediated neutrophil recruitment: Role of glycosaminoglycan interactions
por: Sawant, Kirti V., et al.
Publicado: (2016)

CXCL17 binds efficaciously to glycosaminoglycans with the potential to modulate chemokine signaling
por: Giblin, Sean P., et al.
Publicado: (2023)

Variants of C-C Motif Chemokine 22 (CCL22) Are Associated with Susceptibility to Atopic Dermatitis: Case-Control Studies
por: Hirota, Tomomitsu, et al.
Publicado: (2011)

Chemokine (C-C Motif) Ligand 2 (CCL2) in Sera of Patients with Type 1 Diabetes and Diabetic Complications
por: Guan, Ruili, et al.
Publicado: (2011)

Reduction in Urinary Chemokine (C-C Motif) Ligand 2 (CCL2) After Surgery-Induced Weight Loss
por: Said, Surita Binti, et al.
Publicado: (2020)

Common transcriptional programs and the role of chemokine (C-C motif) ligand 20 (CCL20) in cell migration of cholangiocarcinoma
por: Win Maung, Hay Mar, et al.
Publicado: (2020)

Does C-C Motif Chemokine Ligand 2 (CCL2) Link Obesity to a Pro-Inflammatory State?
por: Dommel, Sebastian, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_reu4m0g8b619ftuudhtseovj03