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Glycogen Synthase Kinase 3 Regulates Cell Death and Survival Signaling in Tumor Cells under Redox Stress()

Targeting tumor-specific metabolic adaptations is a promising anticancer strategy when tumor defense mechanisms are restrained. Here, we show that redox-modulating drugs including the retinoid N-(4-hydroxyphenyl)retinamide (4HPR), the synthetic triterpenoid bardoxolone (2-cyano-3,12-dioxooleana-1,9(...

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Detalles Bibliográficos
Autores principales: Venè, Roberta, Cardinali, Barbara, Arena, Giuseppe, Ferrari, Nicoletta, Benelli, Roberto, Minghelli, Simona, Poggi, Alessandro, Noonan, Douglas M., Albini, Adriana, Tosetti, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4234881/
https://www.ncbi.nlm.nih.gov/pubmed/25246272
http://dx.doi.org/10.1016/j.neo.2014.07.012