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Activation of AMP-activated protein kinase by metformin protects human coronary artery endothelial cells against diabetic lipoapoptosis

BACKGROUND: The prevalence of type 2 diabetes (T2D) among adults worldwide is rapidly increasing, and in patients with diabetes the major cause of death is macrovascular disease. Endothelial cells play an important role in maintaining vascular homeostasis. Free fatty acids, which are elevated in T2D...

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Detalles Bibliográficos
Autores principales:	Eriksson, Linnéa, Nyström, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Original Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4234893/ https://www.ncbi.nlm.nih.gov/pubmed/25391818 http://dx.doi.org/10.1186/s12933-014-0152-5

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