Cargando…

A Rat Model of Striatonigral Degeneration Generated by Simultaneous Injection of 6-Hydroxydopamine into the Medial Forebrain Bundle and Quinolinic Acid into the Striatum

A double toxin-double lesion strategy is well-known to generate a rat model of striatonigral degeneration (SND) such as multiple system atrophy-parkinsonian type. However, with this model it is difficult to distinguish SND from Parkinson's disease (PD). In this study, we propose a new rat model...

Descripción completa

Detalles Bibliográficos
Autores principales: Yoon, Hyung Ho, Kim, Yong Hwan, Shin, Eun Sil, Jeon, Sang Ryong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Academy of Medical Sciences 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4234925/
https://www.ncbi.nlm.nih.gov/pubmed/25408589
http://dx.doi.org/10.3346/jkms.2014.29.11.1555