Cargando…
miR-142 regulates the tumorigenicity of human breast cancer stem cells through the canonical WNT signaling pathway
MicroRNAs (miRNAs) are important regulators of stem and progenitor cell functions. We previously reported that miR-142 and miR-150 are upregulated in human breast cancer stem cells (BCSCs) as compared to the non-tumorigenic breast cancer cells. In this study, we report that miR-142 efficiently recru...
Autores principales: | Isobe, Taichi, Hisamori, Shigeo, Hogan, Daniel J, Zabala, Maider, Hendrickson, David G, Dalerba, Piero, Cai, Shang, Scheeren, Ferenc, Kuo, Angera H, Sikandar, Shaheen S, Lam, Jessica S, Qian, Dalong, Dirbas, Frederick M, Somlo, George, Lao, Kaiqin, Brown, Patrick O, Clarke, Michael F, Shimono, Yohei |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4235011/ https://www.ncbi.nlm.nih.gov/pubmed/25406066 http://dx.doi.org/10.7554/eLife.01977 |
Ejemplares similares
-
Role of epithelial to mesenchymal transition associated genes in mammary gland regeneration and breast tumorigenesis
por: Sikandar, Shaheen S., et al.
Publicado: (2017) -
Single-cell dissection of transcriptional heterogeneity in human colon tumors
por: Dalerba, Piero, et al.
Publicado: (2011) -
Depletion of Trp53 and Cdkn2a Does Not Promote Self-Renewal in the Mammary Gland but Amplifies Proliferation Induced by TNF-α
por: van Weele, Linda J., et al.
Publicado: (2021) -
Serially transplantable mammary epithelial cells express the Thy-1 antigen
por: Lobo, Neethan Amit, et al.
Publicado: (2018) -
MicroRNA-142-3p Negatively Regulates Canonical Wnt Signaling Pathway
por: Hu, Tanyu, et al.
Publicado: (2016)