DAZL Limits Pluripotency, Differentiation, and Apoptosis in Developing Primordial Germ Cells

The scarcity of primordial germ cells (PGCs) in the developing mammalian embryo hampers robust biochemical analysis of the processes that underlie early germ cell formation. Here, we demonstrate that DAZL, a germ cell-specific RNA binding protein, is a robust PGC marker during in vitro germ cell dev...

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Detalles Bibliográficos
Autores principales: Chen, Hsu-Hsin, Welling, Maaike, Bloch, Donald B., Muñoz, Javier, Mientjes, Edwin, Chen, Xinjie, Tramp, Cody, Wu, Jie, Yabuuchi, Akiko, Chou, Yu-Fen, Buecker, Christa, Krainer, Adrian, Willemsen, Rob, Heck, Albert J., Geijsen, Niels
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4235140/
https://www.ncbi.nlm.nih.gov/pubmed/25418731
http://dx.doi.org/10.1016/j.stemcr.2014.09.003

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