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Manipulation of KLF4 Expression Generates iPSCs Paused at Successive Stages of Reprogramming
The detailed mechanism of reprogramming somatic cells into induced pluripotent stem cells (iPSCs) remains largely unknown. Partially reprogrammed iPSCs are informative and useful for understanding the mechanism of reprogramming but remain technically difficult to generate in a predictable and reprod...
Autores principales: | Nishimura, Ken, Kato, Tetsuo, Chen, Chen, Oinam, Lalhaba, Shiomitsu, Emi, Ayakawa, Daisuke, Ohtaka, Manami, Fukuda, Aya, Nakanishi, Mahito, Hisatake, Koji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4235142/ https://www.ncbi.nlm.nih.gov/pubmed/25418733 http://dx.doi.org/10.1016/j.stemcr.2014.08.014 |
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