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Characterization of a Replication-Incompetent Pseudorabies Virus Mutant Lacking the Sole Immediate Early Gene IE180

The alphaherpesvirus pseudorabies virus (PRV) encodes a single immediate early gene called IE180. The IE180 protein is a potent transcriptional activator of viral genes involved in DNA replication and RNA transcription. A PRV mutant with both copies of IE180 deleted was constructed 20 years ago (S....

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Detalles Bibliográficos
Autores principales:	Wu, Brendan W., Engel, Esteban A., Enquist, Lynn W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Microbiology 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4235210/ https://www.ncbi.nlm.nih.gov/pubmed/25389174 http://dx.doi.org/10.1128/mBio.01850-14

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