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Metastable Intermediates as Stepping Stones on the Maturation Pathways of Viral Capsids

As they mature, many capsids undergo massive conformational changes that transform their stability, reactivity, and capacity for DNA. In some cases, maturation proceeds via one or more intermediate states. These structures represent local minima in a rich energy landscape that combines contributions...

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Detalles Bibliográficos
Autores principales: Cardone, Giovanni, Duda, Robert L., Cheng, Naiqian, You, Lili, Conway, James F., Hendrix, Roger W., Steven, Alasdair C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4235213/
https://www.ncbi.nlm.nih.gov/pubmed/25389177
http://dx.doi.org/10.1128/mBio.02067-14