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17β-estradiol upregulates GREB1 and accelerates ovarian tumor progression in vivo

Exogenous 17β-estradiol (E2) accelerates the progression of ovarian cancer in the transgenic tgCAG-LS-TAg mouse model of the disease. We hypothesized that E2 has direct effects on ovarian cancer cells and this study was designed to determine the molecular mechanisms by which E2 accelerates ovarian t...

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Detalles Bibliográficos
Autores principales:	Laviolette, Laura A, Hodgkinson, Kendra M, Minhas, Neha, Perez-Iratxeta, Carol, Vanderhyden, Barbara C
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2014
Materias:	Cancer Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4235304/ https://www.ncbi.nlm.nih.gov/pubmed/24469735 http://dx.doi.org/10.1002/ijc.28741

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