Cargando…

Caffeine stabilizes Cdc25 independently of Rad3 in S chizosaccharomyces pombe contributing to checkpoint override

Cdc25 is required for Cdc2 dephosphorylation and is thus essential for cell cycle progression. Checkpoint activation requires dual inhibition of Cdc25 and Cdc2 in a Rad3-dependent manner. Caffeine is believed to override activation of the replication and DNA damage checkpoints by inhibiting Rad3-rel...

Descripción completa

Detalles Bibliográficos
Autores principales:	Alao, John P, Sjölander, Johanna J, Baar, Juliane, Özbaki-Yagan, Nejla, Kakoschky, Bianca, Sunnerhagen, Per
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2014
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4235345/ https://www.ncbi.nlm.nih.gov/pubmed/24666325 http://dx.doi.org/10.1111/mmi.12592

Ejemplares similares

Caffeine as a tool for investigating the integration of Cdc25 phosphorylation, activity and ubiquitin-dependent degradation in Schizosaccharomyces pombe
por: Alao, John P., et al.
Publicado: (2020)

Caffeine Stabilises Fission Yeast Wee1 in a Rad24-Dependent Manner but Attenuates Its Expression in Response to DNA Damage
por: Alao, John P., et al.
Publicado: (2020)

The ATM and ATR inhibitors CGK733 and caffeine suppress cyclin D1 levels and inhibit cell proliferation
por: Alao, John P, et al.
Publicado: (2009)

The fission yeast FHIT homolog affects checkpoint control of proliferation and is regulated by mitochondrial electron transport
por: Sjölander, Johanna J., et al.
Publicado: (2019)

Cdc18/CDC6 activates the Rad3-dependent checkpoint in the fission yeast
por: Fersht, Naomi, et al.
Publicado: (2007)

CDC5 Inhibits the Hyperphosphorylation of the Checkpoint Kinase Rad53, Leading to Checkpoint Adaptation
por: Vidanes, Genevieve M., et al.
Publicado: (2010)

Characterisation of the SUMO-Like Domains of Schizosaccharomyces pombe Rad60
por: Boyd, Lara K., et al.
Publicado: (2010)

Elevated Levels of the Polo Kinase Cdc5 Override the Mec1/ATR Checkpoint in Budding Yeast by Acting at Different Steps of the Signaling Pathway
por: Donnianni, Roberto Antonio, et al.
Publicado: (2010)

Structural and Functional Insights into the N-Terminus of Schizosaccharomyces pombe Cdc5
por: Collier, Scott E., et al.
Publicado: (2014)

TORC1 Signaling Controls the Stability and Function of α-Arrestins Aly1 and Aly2
por: Bowman, Ray W., et al.
Publicado: (2022)

Therapeutic S and G(2) checkpoint override causes centromere fragmentation in mitosis
por: Stolz, Ailine, et al.
Publicado: (2013)

Cks Overexpression Enhances Chemotherapeutic Efficacy by Overriding DNA Damage Checkpoints
por: del Rincón, Sonia V., et al.
Publicado: (2014)

The Schizosaccharomyces pombe cdc3+ gene encodes a profilin essential for cytokinesis
Publicado: (1994)

Essential Domains of Schizosaccharomyces pombe Rad8 Required for DNA Damage Response
por: Ding, Lin, et al.
Publicado: (2014)

Rad4 Mainly Functions in Chk1-Mediated DNA Damage Checkpoint Pathway as a Scaffold Protein in the Fission Yeast Schizosaccharomyces pombe
por: Yue, Ming, et al.
Publicado: (2014)

Correction: Rad4 Mainly Functions in Chk1-Mediated DNA Damage Checkpoint Pathway as a Scaffold Protein in the Fission Yeast Schizosaccharomyces pombe
por: Yue, Ming, et al.
Publicado: (2018)

Caffeine does not cause override of the G2/M block induced by UVc or gamma radiation in normal human skin fibroblasts
por: Deplanque, G, et al.
Publicado: (2000)

NTRK1/TrkA Activation Overrides the G(2)/M-Checkpoint upon Irradiation
por: Hassiepen, Christina, et al.
Publicado: (2021)

Schizosaccharomyces pombe cdc4+ gene encodes a novel EF-hand protein essential for cytokinesis
Publicado: (1995)

Helicase Subunit Cdc45 Targets the Checkpoint Kinase Rad53 to Both Replication Initiation and Elongation Complexes after Fork Stalling
por: Can, Geylani, et al.
Publicado: (2019)

Nutrient Limitation Inactivates Mrc1-to-Cds1 Checkpoint Signalling in Schizosaccharomyces pombe
por: Fletcher, Jessica, et al.
Publicado: (2018)

Caffeine inhibits gene conversion by displacing Rad51 from ssDNA
por: Tsabar, Michael, et al.
Publicado: (2015)

A Small Molecule Targeting Human MEK1/2 Enhances ERK and p38 Phosphorylation under Oxidative Stress or with Phenothiazines
por: Otręba, Michał, et al.
Publicado: (2021)

Two Distinct Cdc2 Pools Regulate Cell Cycle Progression and the DNA Damage Response in the Fission Yeast S.pombe
por: Caspari, Thomas, et al.
Publicado: (2015)

Suppression of Sensitivity to Drugs and Antibiotics by High External Cation Concentrations in Fission Yeast
por: Alao, John P., et al.
Publicado: (2015)

The S. pombe mitochondrial transcriptome
por: Shang, Jinjie, et al.
Publicado: (2018)

Myocardial Hypertrophy Overrides the Angiogenic Response to Hypoxia
por: Choi, Yeong-Hoon, et al.
Publicado: (2008)

Place learning overrides innate behaviors in Drosophila
por: Baggett, Vincent, et al.
Publicado: (2018)

Verbal instructions override the meaning of facial expressions
por: Bublatzky, Florian, et al.
Publicado: (2018)

Overriding a moral default for honesty or dishonesty
por: Abe, Nobuhito
Publicado: (2020)

The Schizosaccharomyces pombe Checkpoint Kinases Chk1 and Cds1 Are Important for Cell Survival in Response to Cisplatin
por: Paparatto, Domenica, et al.
Publicado: (2009)

Selective inhibition of RET mediated cell proliferation in vitro by the kinase inhibitor SPP86
por: Alao, John P, et al.
Publicado: (2014)

Caffeine suppresses homologous recombination through interference with RAD51-mediated joint molecule formation
por: Zelensky, Alex N., et al.
Publicado: (2013)

Chromosomes with Two Intact Axial Cores Are Induced by G(2 )Checkpoint Override: Evidence That DNA Decatenation Is not Required to Template the Chromosome Structure
por: Andreassen, Paul R., et al.
Publicado: (1997)

Perturbation of cytokinin and ethylene-signalling pathways explain the strong rooting phenotype exhibited by Arabidopsis expressing the Schizosaccharomyces pombe mitotic inducer, cdc25
por: Spadafora, Natasha D, et al.
Publicado: (2012)

Communication between Cyclin-dependent kinase Cdc2 and the Wis1-Spc1 MAPK pathway determines mitotic timing in Schizosaccharomyces pombe
por: Ghosal, Agamani, et al.
Publicado: (2020)

The telomeric transcriptome of Schizosaccharomyces pombe
por: Bah, Amadou, et al.
Publicado: (2012)

S. pombe placed on the prion map
por: Hayles, Jacqueline
Publicado: (2017)

Response to sulfur in Schizosaccharomyces pombe
por: Ohtsuka, Hokuto, et al.
Publicado: (2021)

Overriding of the preseptal orbicularis oculi muscle in Caucasian cadavers
por: Kakizaki, Hirohiko, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_h5he7aekd5s64u11qnj99hr6je