Phenome-wide association study (PheWAS) in EMR-linked pediatric cohorts, genetically links PLCL1 to speech language development and IL5-IL13 to Eosinophilic Esophagitis

Objective: We report the first pediatric specific Phenome-Wide Association Study (PheWAS) using electronic medical records (EMRs). Given the early success of PheWAS in adult populations, we investigated the feasibility of this approach in pediatric cohorts in which associations between a previously...

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Detalles Bibliográficos
Autores principales: Namjou, Bahram, Marsolo, Keith, Caroll, Robert J., Denny, Joshua C., Ritchie, Marylyn D., Verma, Shefali S., Lingren, Todd, Porollo, Aleksey, Cobb, Beth L., Perry, Cassandra, Kottyan, Leah C., Rothenberg, Marc E., Thompson, Susan D., Holm, Ingrid A., Kohane, Isaac S., Harley, John B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4235428/
https://www.ncbi.nlm.nih.gov/pubmed/25477900
http://dx.doi.org/10.3389/fgene.2014.00401

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