An inherited mutation in NLRC4 causes autoinflammation in human and mice

Autoinflammatory syndromes cause sterile inflammation in the absence of any signs of autoimmune responses. Familial cold autoinflammatory syndrome (FCAS) is characterized by intermittent episodes of rash, arthralgia, and fever after exposure to cold stimuli. We have identified a missense mutation in...

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Detalles Bibliográficos
Autores principales: Kitamura, Akiko, Sasaki, Yuki, Abe, Takaya, Kano, Hirotsugu, Yasutomo, Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4235634/
https://www.ncbi.nlm.nih.gov/pubmed/25385754
http://dx.doi.org/10.1084/jem.20141091

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4235634/
https://www.ncbi.nlm.nih.gov/pubmed/25385754
http://dx.doi.org/10.1084/jem.20141091

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