Cytosolic carboxypeptidase CCP6 is required for megakaryopoiesis by modulating Mad2 polyglutamylation

Bone marrow progenitor cells develop into mature megakaryocytes (MKs) to produce platelets for hemostasis and other physiological functions. However, the molecular mechanisms underlying megakaryopoiesis are not completely defined. We show that cytosolic carboxypeptidase (CCP) 6 deficiency in mice ca...

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Detalles Bibliográficos
Autores principales: Ye, Buqing, Li, Chong, Yang, Zhao, Wang, Yanying, Hao, Junfeng, Wang, Li, Li, Yi, Du, Ying, Hao, Lu, Liu, Benyu, Wang, Shuo, Xia, Pengyan, Huang, Guanling, Sun, Lei, Tian, Yong, Fan, Zusen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4235637/
https://www.ncbi.nlm.nih.gov/pubmed/25332286
http://dx.doi.org/10.1084/jem.20141123

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