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Heterogeneity of the Abnormal Prion Protein (PrP(Sc)) of the Chandler Scrapie Strain

The pathological prion protein, PrP(Sc), displays various sizes of aggregates. In this study, we investigated the conformation, aggregation stability and proteinase K (PK)-sensitivity of small and large PrP(Sc) aggregates of mouse-adapted prion strains. We showed that small PrP(Sc) aggregates, previ...

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Detalles Bibliográficos
Autores principales:	Kasai, Kazuo, Iwamaru, Yoshifumi, Masujin, Kentaro, Imamura, Morikazu, Mohri, Shirou, Yokoyama, Takashi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4235706/ https://www.ncbi.nlm.nih.gov/pubmed/25436883 http://dx.doi.org/10.3390/pathogens2010092

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