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The Epithelial-Mesenchymal Transition Factor SNAIL Paradoxically Enhances Reprogramming

Reprogramming of fibroblasts to induced pluripotent stem cells (iPSCs) entails a mesenchymal to epithelial transition (MET). While attempting to dissect the mechanism of MET during reprogramming, we observed that knockdown (KD) of the epithelial-to-mesenchymal transition (EMT) factor SNAI1 (SNAIL) p...

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Detalles Bibliográficos
Autores principales:	Unternaehrer, Juli J., Zhao, Rui, Kim, Kitai, Cesana, Marcella, Powers, John T., Ratanasirintrawoot, Sutheera, Onder, Tamer, Shibue, Tsukasa, Weinberg, Robert A., Daley, George Q.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2014
Materias:	Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4235745/ https://www.ncbi.nlm.nih.gov/pubmed/25316190 http://dx.doi.org/10.1016/j.stemcr.2014.09.008

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