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Role of the Inflammasome-Caspase1/11-IL-1/18 Axis in Cigarette Smoke Driven Airway Inflammation: An Insight into the Pathogenesis of COPD
BACKGROUND: Chronic Obstructive Pulmonary Disease (COPD) is an inflammatory airway disease often associated with cigarette smoke (CS) exposure. The disease is increasing in global prevalence and there is no effective therapy. A major step forward would be to understand the disease pathogenesis. The...
Autores principales: | Eltom, Suffwan, Belvisi, Maria G., Stevenson, Christopher S., Maher, Sarah A., Dubuis, Eric, Fitzgerald, Kate A., Birrell, Mark A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4236128/ https://www.ncbi.nlm.nih.gov/pubmed/25405768 http://dx.doi.org/10.1371/journal.pone.0112829 |
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