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Dicer Is Required for Maintenance of Adult Pancreatic Acinar Cell Identity and Plays a Role in Kras-Driven Pancreatic Neoplasia

The role of miRNA processing in the maintenance of adult pancreatic acinar cell identity and during the initiation and progression of pancreatic neoplasia has not been studied in detail. In this work, we deleted Dicer specifically in adult pancreatic acinar cells, with or without simultaneous activa...

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Detalles Bibliográficos
Autores principales: Wang, Yue J., McAllister, Florencia, Bailey, Jennifer M., Scott, Sherri-Gae, Hendley, Audrey M., Leach, Steven D., Ghosh, Bidyut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4236134/
https://www.ncbi.nlm.nih.gov/pubmed/25405615
http://dx.doi.org/10.1371/journal.pone.0113127