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Regulator of G-Protein Signaling 18 Controls Both Platelet Generation and Function
RGS18 is a myeloerythroid lineage-specific regulator of G-protein signaling, highly expressed in megakaryocytes (MKs) and platelets. In the present study, we describe the first generation of a RGS18 knockout mouse model (RGS18-/-). Interesting phenotypic differences between RGS18-/- and wild-type (W...
Autores principales: | Delesque-Touchard, Nathalie, Pendaries, Caroline, Volle-Challier, Cécile, Millet, Laurence, Salel, Véronique, Hervé, Caroline, Pflieger, Anne-Marie, Berthou-Soulie, Laurence, Prades, Catherine, Sorg, Tania, Herbert, Jean-Marc, Savi, Pierre, Bono, Françoise |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4236145/ https://www.ncbi.nlm.nih.gov/pubmed/25405900 http://dx.doi.org/10.1371/journal.pone.0113215 |
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