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Long-Term Reduction of T-Cell Intracellular Antigens Reveals a Transcriptome Associated with Extracellular Matrix and Cell Adhesion Components

Knockdown of T-cell intracellular antigens TIA1 and TIAR contributes to a cellular phenotype characterised by uncontrolled proliferation and tumorigenesis. Massive-scale poly(A+) RNA sequencing of TIA1 or TIAR-knocked down HeLa cells reveals transcriptome signatures comprising genes and functional c...

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Detalles Bibliográficos
Autores principales: Núñez, Mario, Sánchez-Jiménez, Carmen, Alcalde, José, Izquierdo, José M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4236147/
https://www.ncbi.nlm.nih.gov/pubmed/25405991
http://dx.doi.org/10.1371/journal.pone.0113141