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Denatured Mammalian Protein Mixtures Exhibit Unusually High Solubility in Nucleic Acid-Free Pure Water
Preventing protein aggregation is a major goal of biotechnology. Since protein aggregates are mainly comprised of unfolded proteins, protecting against denaturation is likely to assist solubility in an aqueous medium. Contrary to this concept, we found denatured total cellular protein mixture from m...
Autores principales: | Futami, Junichiro, Fujiyama, Haruna, Kinoshita, Rie, Nonomura, Hidenori, Honjo, Tomoko, Tada, Hiroko, Matsushita, Hirokazu, Abe, Yoshito, Kakimi, Kazuhiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4236158/ https://www.ncbi.nlm.nih.gov/pubmed/25405999 http://dx.doi.org/10.1371/journal.pone.0113295 |
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