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Patterns of Weight Change in Black Americans: Pooled Analysis from Three Behavioral Weight Loss Trials

OBJECTIVE: Differentiating trajectories of weight change and identifying associated baseline predictors can provide insights for improving behavioral obesity treatment outcomes. DESIGN AND METHODS: Secondary, observational analyses using growth mixture models were conducted in pooled data for 604 bl...

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Autores principales: Morales, Knashawn H., Kumanyika, Shiriki K., Fassbender, Jennifer E., Good, Jerene, Localio, A. Russell, Wadden, Thomas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4236267/
https://www.ncbi.nlm.nih.gov/pubmed/25251464
http://dx.doi.org/10.1002/oby.20904
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author Morales, Knashawn H.
Kumanyika, Shiriki K.
Fassbender, Jennifer E.
Good, Jerene
Localio, A. Russell
Wadden, Thomas A.
author_facet Morales, Knashawn H.
Kumanyika, Shiriki K.
Fassbender, Jennifer E.
Good, Jerene
Localio, A. Russell
Wadden, Thomas A.
author_sort Morales, Knashawn H.
collection PubMed
description OBJECTIVE: Differentiating trajectories of weight change and identifying associated baseline predictors can provide insights for improving behavioral obesity treatment outcomes. DESIGN AND METHODS: Secondary, observational analyses using growth mixture models were conducted in pooled data for 604 black American, primarily female adults in three completed clinical trials. Covariates of identified patterns were evaluated. RESULTS: The best fitting model identified three patterns over 2 years: 1) mean weight loss of approximately 2 kg (n=519); 2) mean weight loss of approximately 3 kg at 1 year, followed by ~ 4 kg regain (n=61); and 3) mean weight loss of approximately 20 kg at 1 year followed by ~ 4 kg regain (n=24, with 23 from one study). In final multivariate analyses, higher BMI predicted having pattern 2 (OR[95% CI]) 1.10[1.03, 1.17]) or 3 (OR[95% CI] 1.42[1.25, 1.63]), and higher dietary fat score was predictive of a lower odds of having patterns 2 (OR[95% CI] 0.37[0.15, 0.94]) or 3 (OR[95% CI] 0.23[0.07, 0.79]). CONCLUSIONS: Findings were consistent with moderate, clinically non-significant weight loss as the predominant pattern across all studies. Results underscore the need to develop novel and more carefully targeted and tailored approaches to facilitating weight loss in black American adults.
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spelling pubmed-42362672015-12-01 Patterns of Weight Change in Black Americans: Pooled Analysis from Three Behavioral Weight Loss Trials Morales, Knashawn H. Kumanyika, Shiriki K. Fassbender, Jennifer E. Good, Jerene Localio, A. Russell Wadden, Thomas A. Obesity (Silver Spring) Article OBJECTIVE: Differentiating trajectories of weight change and identifying associated baseline predictors can provide insights for improving behavioral obesity treatment outcomes. DESIGN AND METHODS: Secondary, observational analyses using growth mixture models were conducted in pooled data for 604 black American, primarily female adults in three completed clinical trials. Covariates of identified patterns were evaluated. RESULTS: The best fitting model identified three patterns over 2 years: 1) mean weight loss of approximately 2 kg (n=519); 2) mean weight loss of approximately 3 kg at 1 year, followed by ~ 4 kg regain (n=61); and 3) mean weight loss of approximately 20 kg at 1 year followed by ~ 4 kg regain (n=24, with 23 from one study). In final multivariate analyses, higher BMI predicted having pattern 2 (OR[95% CI]) 1.10[1.03, 1.17]) or 3 (OR[95% CI] 1.42[1.25, 1.63]), and higher dietary fat score was predictive of a lower odds of having patterns 2 (OR[95% CI] 0.37[0.15, 0.94]) or 3 (OR[95% CI] 0.23[0.07, 0.79]). CONCLUSIONS: Findings were consistent with moderate, clinically non-significant weight loss as the predominant pattern across all studies. Results underscore the need to develop novel and more carefully targeted and tailored approaches to facilitating weight loss in black American adults. 2014-09-24 2014-12 /pmc/articles/PMC4236267/ /pubmed/25251464 http://dx.doi.org/10.1002/oby.20904 Text en http://www.nature.com/authors/editorial_policies/license.html#terms Users may view, print, copy, and download text and data-mine the content in such documents, for the purposes of academic research, subject always to the full Conditions of use:http://www.nature.com/authors/editorial_policies/license.html#terms
spellingShingle Article
Morales, Knashawn H.
Kumanyika, Shiriki K.
Fassbender, Jennifer E.
Good, Jerene
Localio, A. Russell
Wadden, Thomas A.
Patterns of Weight Change in Black Americans: Pooled Analysis from Three Behavioral Weight Loss Trials
title Patterns of Weight Change in Black Americans: Pooled Analysis from Three Behavioral Weight Loss Trials
title_full Patterns of Weight Change in Black Americans: Pooled Analysis from Three Behavioral Weight Loss Trials
title_fullStr Patterns of Weight Change in Black Americans: Pooled Analysis from Three Behavioral Weight Loss Trials
title_full_unstemmed Patterns of Weight Change in Black Americans: Pooled Analysis from Three Behavioral Weight Loss Trials
title_short Patterns of Weight Change in Black Americans: Pooled Analysis from Three Behavioral Weight Loss Trials
title_sort patterns of weight change in black americans: pooled analysis from three behavioral weight loss trials
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4236267/
https://www.ncbi.nlm.nih.gov/pubmed/25251464
http://dx.doi.org/10.1002/oby.20904
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