Identification of speckle-type POZ protein somatic mutations in African American prostate cancer

The speckle-type POZ protein (SPOP) is a tumor suppressor in prostate cancer (PCa). SPOP somatic mutations have been reported in up to 15% of PCa of those of European descent. However, the genetic roles of SPOP in African American (AA)-PCa are currently unknown. We sequenced the SPOP gene to identif...

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Detalles Bibliográficos
Autores principales: Buckles, Eric, Qian, Chiping, Tadros, Andrew, Majumdar, Sumana, Cvitanovic, Jennifer, Zabaleta, Jovanny, Estrada, John, Wilson, John, Liu, Wanguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4236324/
https://www.ncbi.nlm.nih.gov/pubmed/24994784
http://dx.doi.org/10.4103/1008-682X.132470

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