Hippocampal changes produced by overexpression of the human CHRNA5/A3/B4 gene cluster may underlie cognitive deficits rescued by nicotine in transgenic mice

Addiction involves long-lasting maladaptive changes including development of disruptive drug-stimuli associations. Nicotine-induced neuroplasticity underlies the development of tobacco addiction but also, in regions such as the hippocampus, the ability of this drug to enhance cognitive capabilities....

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Detalles Bibliográficos
Autores principales: Molas, Susanna, Gener, Thomas, Güell, Jofre, Martín, Mairena, Ballesteros-Yáñez, Inmaculada, Sanchez-Vives, Maria V, Dierssen, Mara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4236452/
https://www.ncbi.nlm.nih.gov/pubmed/25384568
http://dx.doi.org/10.1186/s40478-014-0147-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4236452/
https://www.ncbi.nlm.nih.gov/pubmed/25384568
http://dx.doi.org/10.1186/s40478-014-0147-1

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