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SWI/SNF proteins as targets in cancer therapy

Recent identification of synthetic lethal interactions involving several proteins of the SWI/SNF complex discussed in this Research Highlight has opened the possibility of new cancer therapeutic approaches.

Detalles Bibliográficos
Autores principales: Schiaffino-Ortega, Santiago, Balinas, Carlos, Cuadros, Marta, Medina, Pedro P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4236461/
https://www.ncbi.nlm.nih.gov/pubmed/25391308
http://dx.doi.org/10.1186/s13045-014-0081-5
Descripción
Sumario:Recent identification of synthetic lethal interactions involving several proteins of the SWI/SNF complex discussed in this Research Highlight has opened the possibility of new cancer therapeutic approaches.