Differences in coreceptor specificity contribute to alternative tropism of HIV-1 subtype C for CD4(+) T-cell subsets, including stem cell memory T-cells

BACKGROUND: CD4(+) memory T-cells are a major target for infection by HIV-1, whereby latent provirus can establish and endure suppressive antiretroviral therapies. Although HIV-1 subtype C strains (C-HIV) account for the majority of HIV-1 infections worldwide, the susceptibility of CD4(+) memory T-c...

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Detalles Bibliográficos
Autores principales: Cashin, Kieran, Paukovics, Geza, Jakobsen, Martin R, Østergaard, Lars, Churchill, Melissa J, Gorry, Paul R, Flynn, Jacqueline K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4236466/
https://www.ncbi.nlm.nih.gov/pubmed/25387392
http://dx.doi.org/10.1186/s12977-014-0097-5

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