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Health related quality of life in patients with chronic gastritis and peptic ulcer and factors with impact: a longitudinal study
BACKGROUND: The assessment of Health Related Quality of Life (HRQOL) has been applied as a significant outcome indicator for patients with chronic diseases. No HRQOL study, however, has looked at HRQOL in patients with chronic gastritis and peptic ulcers. This paper focuses on comparing HRQOL in pat...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4236548/ https://www.ncbi.nlm.nih.gov/pubmed/25141760 http://dx.doi.org/10.1186/1471-230X-14-149 |
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author | Wen, Zhengwei Li, Xiaomei Lu, Qian Brunson, Julie Zhao, Miao Tan, Jianfeng Wan, Chonghua Lei, Pingguang |
author_facet | Wen, Zhengwei Li, Xiaomei Lu, Qian Brunson, Julie Zhao, Miao Tan, Jianfeng Wan, Chonghua Lei, Pingguang |
author_sort | Wen, Zhengwei |
collection | PubMed |
description | BACKGROUND: The assessment of Health Related Quality of Life (HRQOL) has been applied as a significant outcome indicator for patients with chronic diseases. No HRQOL study, however, has looked at HRQOL in patients with chronic gastritis and peptic ulcers. This paper focuses on comparing HRQOL in patients with chronic gastritis and peptic ulcers and examining the factors that influence the HRQOL of such patients. Results can be used for making decisions in clinical trials as well as aiding individual management and preventive care of these diseases. METHODS: The Chinese version of the SF-36 (CSF-36) was administered twice to 244 patients with chronic gastritis and peptic ulcers. Mean scores across the two disease groups were compared using t-tests, change over time was analyzed with paired samples t-tests, and factors predicting HRQOL were investigated using the univariate general linear model. RESULTS: The mean domain scores of patients with chronic gastritis were lower than those for patients with peptic ulcers, with the exception of physical functioning. Both groups had lower HRQOL compared with population norms. Mean domain scores increased after treatment in both groups. HRQOL in patients with these two chronic diseases differed by age, education level, marriage, income, and gender, but their explanatory power was relatively low. CONCLUSION: Quality of life of patients with chronic gastritis was lower than that of patients with peptic ulcers, which was lower than population norms. Quality of life in both patients groups was associated with socio-demographic risk factors. |
format | Online Article Text |
id | pubmed-4236548 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-42365482014-11-19 Health related quality of life in patients with chronic gastritis and peptic ulcer and factors with impact: a longitudinal study Wen, Zhengwei Li, Xiaomei Lu, Qian Brunson, Julie Zhao, Miao Tan, Jianfeng Wan, Chonghua Lei, Pingguang BMC Gastroenterol Research Article BACKGROUND: The assessment of Health Related Quality of Life (HRQOL) has been applied as a significant outcome indicator for patients with chronic diseases. No HRQOL study, however, has looked at HRQOL in patients with chronic gastritis and peptic ulcers. This paper focuses on comparing HRQOL in patients with chronic gastritis and peptic ulcers and examining the factors that influence the HRQOL of such patients. Results can be used for making decisions in clinical trials as well as aiding individual management and preventive care of these diseases. METHODS: The Chinese version of the SF-36 (CSF-36) was administered twice to 244 patients with chronic gastritis and peptic ulcers. Mean scores across the two disease groups were compared using t-tests, change over time was analyzed with paired samples t-tests, and factors predicting HRQOL were investigated using the univariate general linear model. RESULTS: The mean domain scores of patients with chronic gastritis were lower than those for patients with peptic ulcers, with the exception of physical functioning. Both groups had lower HRQOL compared with population norms. Mean domain scores increased after treatment in both groups. HRQOL in patients with these two chronic diseases differed by age, education level, marriage, income, and gender, but their explanatory power was relatively low. CONCLUSION: Quality of life of patients with chronic gastritis was lower than that of patients with peptic ulcers, which was lower than population norms. Quality of life in both patients groups was associated with socio-demographic risk factors. BioMed Central 2014-08-20 /pmc/articles/PMC4236548/ /pubmed/25141760 http://dx.doi.org/10.1186/1471-230X-14-149 Text en Copyright © 2014 Wen et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. |
spellingShingle | Research Article Wen, Zhengwei Li, Xiaomei Lu, Qian Brunson, Julie Zhao, Miao Tan, Jianfeng Wan, Chonghua Lei, Pingguang Health related quality of life in patients with chronic gastritis and peptic ulcer and factors with impact: a longitudinal study |
title | Health related quality of life in patients with chronic gastritis and peptic ulcer and factors with impact: a longitudinal study |
title_full | Health related quality of life in patients with chronic gastritis and peptic ulcer and factors with impact: a longitudinal study |
title_fullStr | Health related quality of life in patients with chronic gastritis and peptic ulcer and factors with impact: a longitudinal study |
title_full_unstemmed | Health related quality of life in patients with chronic gastritis and peptic ulcer and factors with impact: a longitudinal study |
title_short | Health related quality of life in patients with chronic gastritis and peptic ulcer and factors with impact: a longitudinal study |
title_sort | health related quality of life in patients with chronic gastritis and peptic ulcer and factors with impact: a longitudinal study |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4236548/ https://www.ncbi.nlm.nih.gov/pubmed/25141760 http://dx.doi.org/10.1186/1471-230X-14-149 |
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