Folate levels measured by LC–MS/MS in patients with colorectal cancer treated with different leucovorin dosages

PURPOSE: Calcium folinate (leucovorin), which is converted in vivo into biologically active folate, enhances the potency of 5-fluorouracil (5-FU)-based chemotherapy in colorectal cancer. A common dosage of leucovorin in adjuvant and palliative settings is 60 mg/m(2). The aim was to determine the lev...

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Detalles Bibliográficos
Autores principales: Taflin, Helena, Wettergren, Yvonne, Odin, Elisabeth, Derwinger, Kristoffer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4236605/
https://www.ncbi.nlm.nih.gov/pubmed/25238909
http://dx.doi.org/10.1007/s00280-014-2591-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4236605/
https://www.ncbi.nlm.nih.gov/pubmed/25238909
http://dx.doi.org/10.1007/s00280-014-2591-9

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