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Folate levels measured by LC–MS/MS in patients with colorectal cancer treated with different leucovorin dosages

PURPOSE: Calcium folinate (leucovorin), which is converted in vivo into biologically active folate, enhances the potency of 5-fluorouracil (5-FU)-based chemotherapy in colorectal cancer. A common dosage of leucovorin in adjuvant and palliative settings is 60 mg/m(2). The aim was to determine the lev...

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Detalles Bibliográficos
Autores principales:	Taflin, Helena, Wettergren, Yvonne, Odin, Elisabeth, Derwinger, Kristoffer
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2014
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4236605/ https://www.ncbi.nlm.nih.gov/pubmed/25238909 http://dx.doi.org/10.1007/s00280-014-2591-9

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