Cargando…

Hepatitis C virus genetics affects miR-122 requirements and response to miR-122 inhibitors

Hepatitis C virus (HCV) replication is dependent on a liver-specific microRNA (miRNA), miR-122. A recent clinical trial reported that transient inhibition of miR-122 reduced viral titers in HCV infected patients. Here we set out to better understand how miR-122 inhibition influences HCV replication...

Descripción completa

Detalles Bibliográficos
Autores principales:	Israelow, Benjamin, Mullokandov, Gavriel, Agudo, Judith, Sourisseau, Marion, Bashir, Ali, Maldonado, Andres Y., Dar, Arvin C., Brown, Brian D., Evans, Matthew J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4236719/ https://www.ncbi.nlm.nih.gov/pubmed/25403145 http://dx.doi.org/10.1038/ncomms6408

Ejemplares similares

Viral Determinants of miR-122-Independent Hepatitis C Virus Replication
por: Hopcraft, Sharon E., et al.
Publicado: (2015)

Regulation of hepatic glutamine metabolism by miR-122
por: Sengupta, Dipanwita, et al.
Publicado: (2020)

miR-155 and miR-122 Expression of Spermatozoa in Obese Subjects
por: López, Paulina, et al.
Publicado: (2018)

Serum levels of miR-29, miR-122, miR-155 and miR-192 are elevated in patients with cholangiocarcinoma
por: Loosen, Sven H., et al.
Publicado: (2019)

Characterization of miR-122-independent propagation of HCV
por: Ono, Chikako, et al.
Publicado: (2017)

Elevated Serum miR-7, miR-9, miR-122, and miR-141 Are Noninvasive Biomarkers of Acute Pancreatitis
por: Lu, Pan, et al.
Publicado: (2017)

Early diagnostic evaluation of miR-122 and miR-224 as biomarkers for hepatocellular carcinoma
por: Amr, Khalda S., et al.
Publicado: (2017)

Metformin decreases miR-122, miR-223 and miR-29a in women with polycystic ovary syndrome
por: Udesen, Pernille Bækgaard, et al.
Publicado: (2020)

Dual Role of miR-122 in Molecular Pathogenesis of Viral Hepatitis
por: Sendi, Hossein
Publicado: (2012)

Plasma miR-122 and miR-3149 Potentially Novel Biomarkers for Acute Coronary Syndrome
por: Li, Xiangdong, et al.
Publicado: (2015)

Role of miR-122 and lipid metabolism in HCV infection
por: Fukuhara, Takasuke, et al.
Publicado: (2012)

Mir-1, miR-122, miR-132, and miR-133 Are Related to Subclinical Aortic Atherosclerosis Associated with Metabolic Syndrome
por: Šatrauskienė, Agnė, et al.
Publicado: (2021)

Circulating microRNAs (miR‐16, miR‐22, miR‐122) expression and early diagnosis of hepatocellular carcinoma
por: Fang, Yujia, et al.
Publicado: (2022)

Various miRNAs compensate the role of miR-122 on HCV replication
por: Ono, Chikako, et al.
Publicado: (2020)

MiR-223-3p and miR-122-5p as circulating biomarkers for plaque instability
por: Singh, Sandeep, et al.
Publicado: (2020)

Microvesicle-associated and circulating microRNAs in diabetic dyslipidemia: miR-218, miR-132, miR-143, and miR-21, miR-122, miR-155 have biomarker potential
por: Nemecz, Miruna, et al.
Publicado: (2023)

MicroRNA-122 Regulation of HCV Infections: Insights from Studies of miR-122-Independent Replication
por: Panigrahi, Mamata, et al.
Publicado: (2022)

Miravirsen (SPC3649) can inhibit the biogenesis of miR-122
por: Gebert, Luca F. R., et al.
Publicado: (2014)

Synergistic anticancer effects of nanocarrier loaded with berberine and miR-122
por: Li, Lei, et al.
Publicado: (2018)

miR-122 and hepatocellular carcinoma: from molecular biology to therapeutics
por: Fu, Xiao, et al.
Publicado: (2018)

The Roles of Epinephelus coioides miR-122 in SGIV Infection and Replication
por: Sun, Hong-Yan, et al.
Publicado: (2021)

miR−122−5p Regulates Renal Fibrosis In Vivo
por: Kaneko, Shohei, et al.
Publicado: (2022)

Nuclear miR-122 directly regulates the biogenesis of cell survival oncomiR miR-21 at the posttranscriptional level
por: Wang, Dong, et al.
Publicado: (2018)

Potential relative quantities of miR-122 and miR-150 to differentiate hepatocellular carcinoma from liver cirrhosis
por: Gumilas, Nur Signa Aini, et al.
Publicado: (2022)

miR-122-5p regulates the tight junction of the blood-testis barrier of mice via occludin: miR-122-5p can regulate the tight junction
por: Liu, Limin, et al.
Publicado: (2021)

Resveratrol and EGCG bind directly and distinctively to miR-33a and miR-122 and modulate divergently their levels in hepatic cells
por: Baselga-Escudero, Laura, et al.
Publicado: (2014)

The effects of hepatitis C virus core protein on the expression of miR-122 in vitro
por: Li, Sujuan, et al.
Publicado: (2013)

Enhancement of hepatitis C viral RNA abundance by precursor miR-122 molecules
por: Cox, Erica Machlin, et al.
Publicado: (2013)

MicroRNAs and hepatitis C virus: Toward the end of miR-122 supremacy
por: Hoffmann, Thomas Walter, et al.
Publicado: (2012)

MiR-19a, miR-122 and miR-223 are differentially regulated by hepatitis B virus X protein and involve in cell proliferation in hepatoma cells
por: Yu, Guifang, et al.
Publicado: (2016)

miR33a/miR33b* and miR122 as Possible Contributors to Hepatic Lipid Metabolism in Obese Women with Nonalcoholic Fatty Liver Disease
por: Auguet, Teresa, et al.
Publicado: (2016)

Kinetics of miR-122 Expression in the Liver during Acute HCV Infection
por: Choi, Youkyung, et al.
Publicado: (2013)

miR-122 Regulates Tumorigenesis in Hepatocellular Carcinoma by Targeting AKT3
por: Nassirpour, Rounak, et al.
Publicado: (2013)

Serum miR-122 correlates with short-term mortality in sepsis patients
por: Wang, Huijuan, et al.
Publicado: (2014)

Decreased miR122 in hepatocellular carcinoma leads to chemoresistance with increased arginine
por: Kishikawa, Takahiro, et al.
Publicado: (2015)

miR-122 promotes diabetic retinopathy through targeting TIMP3
por: Wang, Mingliang, et al.
Publicado: (2020)

MiR-122 Promotes the Development of Colon Cancer by Targeting ALDOA In Vitro
por: Li, Hong, et al.
Publicado: (2019)

miR-122 Inhibits Hepatocarcinoma Cell Progression by Targeting LMNB2
por: Li, Xiao-Na, et al.
Publicado: (2020)

ADAR2-Mediated Editing of miR-214 and miR-122 Precursor and Antisense RNA Transcripts in Liver Cancers
por: Liu, Wan-Hsin, et al.
Publicado: (2013)

Clinical Significance of Circulating miR-1273g-3p and miR-122-5p in Pancreatic Cancer
por: Mazza, Tommaso, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_4fv55q0vallhoi5hibuvotom3m