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Transcriptomic profiling of splenic B lymphomas spontaneously developed in B cell-specific TRAF3-deficient mice

TRAF3, a critical regulator of B cell survival, was recently recognized as a tumor suppressor gene in B lymphocytes. Specific deletion of TRAF3 from B lymphocytes leads to spontaneous development of marginal zone lymphomas (MZL) or B1 lymphomas in mice. To identify novel oncogenes and tumor suppress...

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Detalles Bibliográficos
Autores principales: Xie, Ping, Moore, Carissa R., Swerdel, Mavis R., Hart, Ronald P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4236829/
https://www.ncbi.nlm.nih.gov/pubmed/25419513
http://dx.doi.org/10.1016/j.gdata.2014.10.017