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Common gamma chain (γc) cytokines differentially potentiate TNFR family signaling in antigen-activated CD8(+) T cells

BACKGROUND: Several members of the common gamma chain (gc) cytokine family are already approved (IL-2) or actively being developed as vaccine adjuvants and cancer immunotherapies. Studies have indicated that co-administration of gc cytokines may enhance the efficacy of immunotherapies that function...

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Detalles Bibliográficos
Autores principales: McNamara, Michael J, Kasiewicz, Melissa J, Linch, Stefanie N, Dubay, Christopher, Redmond, William L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4236884/
https://www.ncbi.nlm.nih.gov/pubmed/25411639
http://dx.doi.org/10.1186/s40425-014-0028-y