The API2-MALT1 Fusion Exploits TNFR Pathway-associated RIP1 Ubiquitination to Promote Oncogenic NF-κB Signaling

The API2-MALT1 fusion oncoprotein is created by the recurrent t(11;18)(q21;q21) chromosomal translocation in mucosa-associated lymphoid tissue (MALT) lymphoma. We identified receptor interacting protein-1 (RIP1) as a novel API2-MALT1-associated protein and demonstrate that RIP1 is required for API2-...

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Detalles Bibliográficos
Autores principales: Rosebeck, Shaun, Rehman, Aasia O., Apel, Ingrid J., Kohrt, Dawn, Appert, Alex, O’Donnell, Marie Anne, Ting, Adrian T., Du, Ming-Qing, Baens, Mathijs, Lucas, Peter C., McAllister-Lucas, Linda M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237018/
https://www.ncbi.nlm.nih.gov/pubmed/23770847
http://dx.doi.org/10.1038/onc.2013.195

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